Name: THAIZ SCHEIDEGGER DE SOUZA
Publication date: 12/12/2024
Examining board:
Name |
Role |
|---|---|
| ADRIANO FORTES MAIA | Presidente |
| DANILO SALES BOCALINI | Coorientador |
| LUCAS GUIMARÃES FERREIRA | Examinador Externo |
| RODRIGO FREIRE DE ALMEIDA | Examinador Externo |
Summary: High-intensity interval exercise (HIIE) is an effective strategy to enhance physical fitness, offering practicality, low cost, and no need for specialized equipment. However, its high intensity may lead to intramuscular acidosis caused by the accumulation of hydrogen ions (H+ ), contributing to muscle fatigue. Sodium bicarbonate (NaHCO3) has been studied for its ability to buffer extracellular acidosis and improve physical performance. This study investigated the effects of NaHCO3 supplementation on 12 healthy adult men during HIIE sessions, using a crossover, randomized design with two protocols: (1) HIIE with NaHCO3 supplementation (0.3 g/kg body mass) and (2) HIIE with placebo (calcium carbonate). Assessments were conducted at four time points: baseline, pre-, immediately post-, and 24 hours post- exercise. Blood samples were collected to analyze glucose, triglycerides, uric acid, TNF-alpha, IL-10, total protein, albumin, HDL-cholesterol, total cholesterol, and lactate. Statistical analyses included repeated-measures ANOVA with post hoc tests. The results showed that NaHCO3 supplementation significantly increased blood bicarbonate levels before and during exercise. Although no statistically significant differences were found in biochemical markers such as creatine kinase (CK) and lactate, trends of improvement were observed in the supplemented group. Inflammatory markers indicated an increase in IL-10 and a reduction in TNF-alpha, suggesting an anti-inflammatory effect. The supplementation was well-tolerated and did not present statistically significant gastrointestinal effects.These findings reinforce the ergogenic and anti-inflammatory potential of NaHCO3 during HIIE sessions. However, limitations such as the small sample size and the absence of statistical significance in some parameters highlight the need for future research to explore alternative supplementation protocols and better understand individual responses to NaHCO3 use during high-intensity exercise.
Keywords: HIIE; sodium bicarbonate; supplementation; inflammation; performance.
